Metformin Hcl Ip/bp/ep/usp

Here are the specifications for Metformin Hydrochloride according to various pharmacopeias (IP, BP, EP, USP):

Chemical Name: Metformin hydrochloride
Molecular Formula: C4H11N5HCl
Molecular Weight: Approximately 165.62 g/mol
Drug Class: Biguanide antidiabetic agent
Mechanism of Action: Reduces hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Indications: Treatment of type 2 diabetes mellitus, particularly in overweight patients when dietary management and exercise alone have not been effective.
Dosage Form: Oral tablets
Dosage: Initial dose typically ranges from 500 mg to 1000 mg daily, gradually titrated based on blood glucose levels and patient response.
Appearance: White to off-white crystalline powder.
Solubility: Freely soluble in water; practically insoluble in acetone, ether, and chloroform